Antibody-based drugs and vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being expedited through preclinical and clinical development. Data from the study of SARS-CoV and other respiratory viruses suggest that anti-SARS-CoV-2 antibodies could exacerbate COVID-19 thr …

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Here we confirmed that BNT162b2 vaccination of healthy individuals induced effective humoral and cellular immunity against several SARS-CoV-2 variants. Interestingly, however, the BNT162b2 vaccine also modulated the production of inflammatory cytokines by innate immune cells upon stimulation with both specific (SARS-CoV-2) and non-specific (viral, fungal and bacterial) stimuli. The response of innate immune cells to TLR4 and TLR7/8 ligands was lower after BNT162b2 vaccination, while fungi-induced cytokine responses were stronger. In conclusion, the mRNA BNT162b2 vaccine induces complex functional reprogramming of innate immune responses, which should be considered in the development and use of this new class of vaccines.

/PRNewswire/ -- Of the 700 physicians responding to an internet survey by the Association of American Physicians and Surgeons (AAPS), nearly 60 percent said...

In just a few months, the World Health Organization received approximately 20,000 reports of new eye disorders that occurred post covid-19 vaccination. These reports include 303 cases of blindness and 1,625 cases of visual impairment! The European drug monitoring agency had never recorded such a severe spike in eye injuries until after the experimental vaccines […]

Researchers find that surges in COVID-19 case numbers are associated with deletions in the SARS-CoV-2 genome in an antigenic site of the spike protein. Some of these mutations are present in vaccine breakthrough infections or reinfections.

A Freedom of Information request to the Australian drugs regulator that approved the Pfizer vaccine confirms that they have never seen the study data.