Scientific Reports - Association between vitamin D supplementation and COVID-19 infection and mortality

Background Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available. Results We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations. Conclusion Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.

A board-certified family medical physician who works with Dr. George Fareed in California’s Imperial Valley, Dr. Brian Tyson states that, based on his work with more than 6,000 Covid patients, 70% of all cases nationwide could have been saved using his early-treatment methods. Dr. Tyson has based his methods, which employ FDA-approved drugs, on fourteen years of experience in the emergency room and another ten years in the ICU. He also states that he hasn’t lost a single patient who has come to him during the first week of having contracted Covid.

Regular use of ivermectin as a prophylactic was associated with significantly reduced COVID-19 infection, hospitalization and mortality rates.

Overall, the state has a total of 199 active cases, while the positivity rate came down to less than 0.01 per cent.